By José María Fernández-Rúa, a team of twelve researchers from four U.S. universities have managed to identify the molecular mechanism by which asbestos causes cancer. This finding, published in “Proceedings”, organ of the Academy of Sciences of the United States, opens the way to achieve methods of treatment for malignant mesothelioma (cancer of the pleura), one of the main caused by asbestos.
Michael Carbone of Loyola University in Chicago has found that asbestos triggers the inflammatory protein tumor necrosis factor alpha, which causes cell damage. Asbestos has been used in many countries, including Spain, in a variety of manufactures, such as building materials, clutches and brakes for automobiles, packaging, textiles and carpeting, to its ban earlier this century.
This research undoubtedly important to identify potential targets in the future acting drugs, it also opens the door to confirm that asbestos is the origin of other carcinomas, including stomach, colon and larynx. On this last cancer, the U.S. Senate a few weeks ago concluded that asbestos gives rise to its appearance, after the adoption of a comprehensive report by the National Institutes of Health at the request of a large group of workers with this disease that for years, were working with materials containing asbestos. The Senate will probably approve before the end of the year a compensation fund for injuries caused by this mineral, amounting to $ 140,000. Asbestos mainly affects the lungs and pleura, a membrane that surrounds these bodies. Thus, breathing high levels of asbestos fibers can cause long lesions that resemble scars in the lung.
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